Study your flashcards anywhere!

Download the official Cram app for free >

  • Shuffle
    Toggle On
    Toggle Off
  • Alphabetize
    Toggle On
    Toggle Off
  • Front First
    Toggle On
    Toggle Off
  • Both Sides
    Toggle On
    Toggle Off
  • Read
    Toggle On
    Toggle Off
Reading...
Front

How to study your flashcards.

Right/Left arrow keys: Navigate between flashcards.right arrow keyleft arrow key

Up/Down arrow keys: Flip the card between the front and back.down keyup key

H key: Show hint (3rd side).h key

A key: Read text to speech.a key

image

Play button

image

Play button

image

Progress

1/52

Click to flip

52 Cards in this Set

  • Front
  • Back

formation of a blood clot

thrombosis

the blot clot

thrombus

thrombus that detaches from a blood vessels wall and travels through the blood stream

embolus

complex process by which fibrin forms and blood clots

hemostasis

When a blood vessel is injured, a series of events occurs to form a clot and stop the bleeding; this process is called _______

hemostasis

It involves a complex process called the ____ ___

coagulation cascade

When the thrombus detaches itself from the wall of the vessel and is carried along through the bloodstream, it becomes an _____

embolus

IF the embolus goes to the lung and obstructs a pulmonary vessel, it is called ____ ___

pulmonary embolism

____ drugs prevent the formation of clots

anticoagulation

drugs that suppress platelet aggregation

antiplatelet

drugs that help to eliminate the clot

thrombolytics

Anticoagulants have no ___ effect on an existing thrombus and do not reverse any damage from the thrombus

direct

The drug taken orally for anticoagulation is

warfarin (Coumadin)

The drugs used parenterally are

Heparin




heparin sodium




enoxaparin (Lovenox)

peak activity for warfarin is __-__ days after therapy is initiated

1-3

Anticoagulants prevent the formations of extension of a ___, maintain potency of intravenous catheters, ____ for cardiovascular conditions

thrombus




prophylaxis

The common adverse reactions for anticoagulants are mild to severe ___, bruising, and petechiae. Aslo rash and ____

bleeding




hives

What are come drugs you would not want to give with an anticoagulant that would increase the risk for bleed?

aspirin




PCN, aminoglycosides, tetracylcines, cephalosporins




Beta blockers




Drugs for GI bleed

an overdose of coumadin can cause hemorrhage, headache, ____ and back pain

bruising

uses for coumadin are

clot formation for DVT




PE




A fib with embolism,




TIA


Coronary occlusion problems

_____ interferes with vitamin K dependent clotting factors and reduces prothrombin

Warfarin (Coumadin)

WHen on Warfarin take __ and __ daily until stable and then every 4-6 weeks

PT




INR

____ interferes with warfarin (coumadin)

vitamin K

high dietary amounts of vitamin K ___ effect and increase clot formation

decrease

Too much warfarin, ETOH, ASA can ___ effects and increase the risk of bleeding

increase

These foods have a High potential to interact with these foods/herbs and increase the risk for bleeding:

Celery, garlic


Chamomile


Clove, ginger


ginseng, ginkgo biloba


feverfew, passion flower, red clover,


Green Tea


Dong quai

Heparin solutions inhibit the formation of ___ clots, inhibit conversion of ___ to fibrin, and inactivate clotting factor ___ and thrombin

fibrin




fibrinogen




Xa

What are the heparins?

heparin




Heparin sodium flush lock (Hep-Lock)




Enoxaparin (Low molecular wt heparins)



Heparin solutions are given in ____

units

The routes for heparins are

IV




SQ

___ and ____ are taken daily to adjust the dose as needed

PTT




aPTT

Heparin does not lyse or _____ up clots, it just delays their formation

break

When giving heparin SQ angle the needle at __-__ angle and the needle size is __-___ gauge 3/8" to 1"

45-90 degree




25-30

The site used to administer heparin is the _____, upper arm, and upper thigh

abdomen

No aspiration once needle is _____

inserted

No rubbing at the ___ after injection

site

When monitoring PTT/aPTT for heparin therapy, the therapeutic range is __-___ times the normal

1.5-2.5

PT and INR while monitoring Coumadin therapy has a therapeautic range __-___ times the control value

1.2-1.5

If PT is greater than 2.5 times the control value, or INR is greater than 4, the person will have ___ tendencies

bleeding

When reading the labs, the higher the number the slower the ___

clot

A nurse should monitor PT/INR until stable and with prescribed therapeutic range. ONgoing lab evaluations are every _-__ weeks

4-6

You will withhold the drug is PT is greater than __-___ times the control value or INR is over 3 or if there is evidence of bleeding

1.2-1.5

With heparin, ____ the dose according to daily aPTT monitoring

adjust

___ is used for warfarin overdose

vitamin K

Anitplatelet drugs ___ platelet aggregation

prevent

some examples of antiplatelet drugs:

plavix




Xarelto




Persantine

These are given

PO

adverse reactions of antiplatelet drugs

heart palaptions


Bleeding


dizz and HA


ND, constipation, dyspepsia

These drugs work by ____ the platelets ability to stick together in the blood, thus forming a clot

decreasing

_____ drugs dissolves (lysis) all existing blood clots inside vessels

thrombolytics

examples of thrombolytics are

alteplase recombinant (Activase)


streptokinase (Streptase)


tenecteplase (TNKase)

Thrombolytics are administered

IV